Hello and thank you for reaching out, that’s a great question!
Different people will require different amounts of applications based on their current needs or conditions. The inventor of the product and current founder of the company originally applied it multiple times throughout the day when their skin condition was severe and dry. Now, they only apply it a couple of times a week to maintain the recovered condition. On a general basis, we recommend applying it twice a day, once in the morning & once at night. When applying we recommend three sprays each application with a couple of moments for it to rest between each spray for it to create layers. Please feel free to use it as needed, as there are currently no negative side effects known after thorough testing. Though to be safe and for legal purposes, if irritation occurs please stop use immediately.